Update, 11/28/16: Took PANRE 1 month ago and aced it. This was the first time I took the test without touching a physical book. This app and some additional reading was all I did. See older review below.
This app is pretty much all you need to pass the PANCE or PANRE on condition that you do SOME additional reading. I found that using the app and quickly googling/referring to my Merck Manual app/other resources right on my iPhone...was a perfect way to consolidate what I was studying and often to get better/more well-rounded information. Make no mistake, this app covers ALL the critical data you need to know for the generalist exam. Its your job to round off your understanding with additional reading. That additional reading added maybe 2-3 minutes for each question at most, given how blessed we are to live in the digital age with knowledge at our fingertips.
Now for the cons. There are several minor typos but I havent found any actual medically incorrect information. Perhaps I missed it, I dont know.
Why use the app over a physical book? Because it gives you real time answers, tracks your progress, grades your work, shows you your strengths and weaknesses. It has a feature that maps and graphs your progress with data regarding your individual and overall scores along with scores for each section. It also tells you how much of time you spent on average per question. Thats priceless. Regarding the errors, Ive contacted the developer often and the responses were pretty fast. Use the "report a problem" link inside the app. Its buried under the icon on the bottom left that looks like a stack of pages.
Highly recommended
Mikmeister about Physician Assistant Boards Q&A, v1.6